Özgür Yılmaz Beker

I am a CS PhD student in the MorphoLab, located in the Department of Statistics at Columbia University, where I am extremely fortunate to be advised by Bianca Dumitrascu to work on cool problems related to computational biology.

During my undergraduate studies, I was introduced to computational biology through a joint project in the Adebali and Mustafaoglu labs, where I worked with bulk RNA-Seq data from the blood-brain barrier; this eventually gave rise to the Brendo resource. I also interned at EMBL-EBI as part of the Papatheodorou Group, where I contributed to the codebase of CATD Snakemake.

After earning my B.S. in Computer Science and Engineering from Sabancı University, I worked as a Graduate Research Assistant with the Irving Institute for Cancer Dynamics, helping start the Ladder framework for modeling single-cell data obtained from multiple experimental conditions.

Email  /  GitHub  /  Google Scholar  /  ORCID

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Ladder - probabilistic modeling of single-cell omics data

Ladder is a probabilistic modeling framework developed mainly for single-cell omics data. It is under active development; check out the GitHub page for more updates soon.

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Variational Learning of Disentangled Representations


Yuli Slavutsky*, Ozgur Beker*, David Blei, Bianca Dumitrascu
ICML, 2026
paper / arxiv / code /

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Patches: A Representation Learning Framework for Decoding Shared and Condition-Specific Transcriptional Programs in Wound Healing


Ozgur Beker, Simon Van Deursen, Michel Tarnow, Dreyton Amador, Jonathan Chin Cheong, Jose Francisco Pomarino Nima ProfileMark D. Robinson, Yvon Woappi, Bianca Dumitrascu
bioRxiv, 2024
arxiv / code / website /




Biophysical modeling for morphodynamics

This section is still under construction; check in again soon.

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Single-cell morphodynamics predict cell fate decisions during mucociliary epithelial differentiation


Mari Tolonen, Ziwei Xu, Ozgur Beker, Varun Kapoor, Bianca Dumitrascu & Jakub Sedzinski
Molecular Systems Biology, 2026
paper / code /




Past projects

Projects I worked on in the past.

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Brendo: an open resource for uniquely transcribed genes in brain endothelial cells


Ozgur Beker, Fereshteh Ramezani Khorsand, Ogun Adebali, Nur Mustafaoglu
bioRxiv, 2025
arxiv / code / website /

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CATD: a reproducible pipeline for selecting cell-type deconvolution methods across tissues


Anna Vathrakokoili Pournara , Zhichao Miao , Ozgur Yilimaz Beker, Nadja Nolte , Alvis Brazma , Irene Papatheodorou
Bioinformatics Advances, 2024
paper / code /


Design and source code from Jon Barron's website